The TeleQuit MH dataset was collected for a type-II hybrid effectiveness-implementation study that evaluated a smoking cessation telephone care program for mental health patients in the Veterans Health Administration (VHA). The primary objectives were to evaluate the adaption, implementation, and maintenance of the smoking cessation program; determine its effectiveness at long-term abstinence; and...

The Consortium of Hospitals Advancing Research on Tobacco (CHART) is a network of six projects and a coordinating center aimed at assessing the effectiveness and cost-effectiveness of smoking cessation interventions initiated during hospitalizations and continued post-discharge. The CHART New York Smoking-Cessation Interventions for Urban Hospital Patients trial looked at the effectiveness of a pro-active,...

This dataset was generated from a 12-month two-arm cluster-randomized controlled trial, Counseling African Americans to Control Hypertension (CAATCH). The goal of the study was to evaluate the effectiveness of a multilevel, multicomponent, evidence-based intervention compared with usual care in improving blood pressure control among hypertensive blacks who receive care in community health centers....

The Financial Incentives for Weight Reduction (FIReWoRk) trial assessed the comparative effectiveness of financial incentives on the attainment of weight loss goals among adult patients (aged 18 to 70 years old) with obesity from neighborhoods with low socioeconomic status in New York City and Los Angeles. Eligible patients were identified at 3 primary care locations: NYC Health+Hospitals – Bellevue,...

The dataset includes a total of 757 patients with uncontrolled hypertension who were enrolled into the Task Shifting and Blood Pressure Control in Ghana (TASSH) study through 32 community health centers in Ghana. TASSH was a randomized controlled trial that compared the outcomes of 2 interventions to reduce systolic blood pressure (SBP): standard of care treatment available through public health insurance...

In a pilot open-label randomized controlled trial, investigators compared the effectiveness and acceptability of buprenorphine extended-release (XRB) drugs versus daily sublingual buprenorphine-naloxone (SLB) to treat opioid use disorders in adult prisoners during incineration and after community re-entry. Eligible participants met the following inclusion criteria: Over 18 years old Met Diagnostic...

Survey and clinical data were obtained from 570 participants in a randomized controlled trial to evaluate the comparative effectiveness of an extended release injectable naltrexone (XR-NTX, Vivitrol®) against buprenorphine-naloxone (BUP-NX, Suboxone®) as treatments for opioid dependence. The study was conducted in 8 NIDA Clinical Trials Network-affiliated community treatment programs in the United...

The CariedAway project was a cluster randomized pragmatic clinical trial that investigated the non-inferiority of silver diamine fluoride (SDF) versus glass ionomer sealants in the arrest and incidence of dental caries in children when applied through a school-based oral disease prevention program. Secondary objectives of the CariedAway trial were to (1) assess the non-inferiority of SDF when applied...

Accelerating COVID-19 Therapeutic Interventions and Vaccines 4 ACUTE (ACTIV4A) is a randomized, open label, adaptive platform trial that compares the effectiveness of several antithrombotic strategies for the prevention of adverse outcomes in COVID-19 positive inpatients. Investigators assessed outcomes such as the number of days that a patient is alive and free of organ support through the first 21...